These Rare and Unique Substructures adhere to the Rule of Three (FW<300, <3 rotatable bonds, ClogP<3). The functional groups that do not react with protein. These are ideal for Fragment-Based Lead Discovery and subsequent optimization.
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
228 |
6-Aminooxy-hexanoic acid; hydrobromide (Purity >95%)
At least 25 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
295 |
495 |
1495 |
3950 |
|
|
|
|
 |
188 |
4-(Difluoromethoxy)-phenylboronic acid (Purity >95%)
At least 10 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
295 |
495 |
1350 |
3995 |
|
|
|
|
 |
211 |
4-Vinyl-piperidine-1-carboxylic acid tert-butyl ester (Purity >95%)
|
| Special Order: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
|
895 |
1495 |
3495 |
|
|
|
|
 |
151 |
2,6-Dimethyl-pyridine-4-boronic acid (Purity >95%)
At least 7.44 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
295 |
395 |
950 |
2495 |
4995 |
|
|
|
|
 |
124 |
O-Cyclobutyl-hydroxylamine hydrochloride
(Purity >95%)
At least 1 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
395 |
895 |
2995 |
5995 |
|
|
|
|
 |
152 |
O-(2,2,2-Trifluoroethyl)hydroxylamine hydrochloride (Purity >93%)
At least 22 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
245 |
595 |
895 |
3995 |
6995 |
|
|
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
172 |
4-Difluoromethyl-phenylboronic acid (Purity >95%)
At least 5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
495 |
895 |
1995 |
4995 |
|
|
|
|
 |
188 |
3-(Difluoromethoxy)-benzeneboronic acid (Purity >95%)
At least 75 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
195 |
395 |
950 |
2495 |
4995 |
6995 |
|
|
|
 |
144 |
5-Chloro-3,4-diaminopyridine (Purity >95%)
At least 25 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
295 |
395 |
850 |
1995 |
3995 |
6995 |
|
|
|
 |
211 |
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isothiazole (Purity >95%)
At least 1 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
850 |
1495 |
2990 |
|
|
|
|
|
 |
178 |
4-Bromo-3-methyl-isothiazole (Purity >95%)
At least 5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
495 |
895 |
2295 |
|
|
|
|
|
 |
106 |
But-3-ynylamine hydrochloride (Purity >95%)
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
395 |
1495 |
5495 |
|
|
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
188 |
5-Bromo-3,4-diaminopyridine (Purity >95%)
At least 50 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
495 |
950 |
1995 |
2995 |
3995 |
|
|
|
 |
162 |
4-Cyclopropyl-phenylboronic acid (Purity >95%)
At least 32 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
495 |
1895 |
3995 |
8990 |
|
|
|
 |
191 |
5-Trifluoromethyl-pyridine-3-boronic acid (Purity >95%)
At least 5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
395 |
895 |
3995 |
8995 |
|
|
|
|
 |
266 |
4,4,5,5-Tetramethyl-2-(1,4-dioxaspiro[4.5]dec-7-en-7-yl)-1,3,2-dioxaborolane (Purity >95%)
At least 24 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
495 |
1995 |
4995 |
|
|
|
|
 |
222 |
5-Biphenyl-3-yl-2H-tetrazole (Purity >99%)
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
145 |
295 |
495 |
1995 |
|
|
|
|
|
 |
108 |
3-Azetidinone hydrochloride (Purity >95%)
At least 0.9 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
495 |
795 |
2295 |
3995 |
|
|
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
180 |
(6,7-Dihydro-4H-pyrano[4,3-d]thiazol-2-yl)-acetonitrile (Purity >95%)
At least 0.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
190 |
305 |
870 |
3625 |
|
|
|
|
|
 |
111 |
(1-Hydroxymethyl-cyclopropyl)-acetonitrile (Purity >95%)
At least 10 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
|
295 |
795 |
1950 |
|
|
|
|
 |
266 |
6-Bromo-2-trifluoromethyl-3H-imidazo[4,5-b]pyridine (Purity >95%)
At least 14.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
125 |
245 |
495 |
1995 |
3995 |
|
|
|
|
 |
223 |
6-Bromo-pyrazolo[1,5-a]pyrimidine-3-carbonitrile (Purity >95%)
At least 4.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
295 |
495 |
895 |
2995 |
4995 |
|
|
|
|
 |
202 |
2,2-Difluoro-benzo[1,3]dioxole-5-boronic acid (Purity >95%)
At least 1 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
395 |
850 |
2495 |
4995 |
|
|
|
|
 |
151 |
3-Aminoisothiazolo[3,4-b]pyridine (Purity >95%)
At least 10 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
295 |
595 |
950 |
1995 |
6495 |
|
|
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
200 |
4-(aminooxy)butanoic acid, hydrobromide (Purity >90%)
At least 10 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
80 |
95 |
195 |
950 |
2950 |
|
|
|
|
 |
214 |
5-(aminooxy)pentanoic acid, hydrobromide (Purity >90%)
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
80 |
95 |
195 |
950 |
2950 |
|
|
|
|
 |
118 |
6-Azaindole (Purity >95%)
At least 40 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
75 |
95 |
195 |
850 |
1950 |
|
|
|
|
 |
148 |
7-Azaisatin (Purity >95%)
At least 0.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
495 |
995 |
4495 |
7495 |
|
|
|
|
 |
214 |
2-Azetidin-1-yl-5-bromo-pyrimidine (Purity >95%)
At least 5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
195 |
595 |
850 |
2995 |
7995 |
|
|
|
|
 |
178 |
1-Benzothien-7-ylboronic acid (Purity >95%)
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
|
895 |
3495 |
7995 |
|
|
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
319 |
4-(Benzo[b]thiophene-3-sulfonyl)-piperazine hydrochloride (Purity >95%)
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
175 |
|
|
|
|
|
|
|
 |
273 |
2-(Boc-amino)-4-bromopyridine (Purity >95%)
At least 19 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
125 |
250 |
495 |
1995 |
3995 |
|
|
|
|
 |
197 |
N-Boc-3-Methylene-piperidine (Purity >95%)
At least 5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
|
495 |
1995 |
3995 |
|
|
|
|
 |
255 |
5-Bromo-1,1-(ethylenedioxo)-indane (Purity >95%)
At least 19.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
295 |
495 |
1995 |
4995 |
|
|
|
|
 |
213 |
3-Bromo-1-methyl-1,2,5,6-tetrahydropyridine hydrochloride (Purity >95%)
At least 15 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
295 |
495 |
2295 |
4495 |
|
|
|
|
 |
214 |
6-Bromo-1H-imidazo[4,5-b]pyridin-2(3H)-one (Purity >95%)
At least 19.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
495 |
1995 |
2995 |
|
|
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
198 |
7-Bromo-1H-imidazo[4,5-c]pyridine (Purity >95%)
At least 5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
295 |
495 |
1995 |
4995 |
|
|
|
|
 |
229 |
7-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one (Purity >95%)
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 195 |
495 |
995 |
1995 |
2995 |
5995 |
|
|
|
|
 |
239 |
7-Bromo-2,4-diaminoquinazoline (Purity >95%)
At least 10 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
145 |
245 |
495 |
2295 |
3995 |
|
|
|
|
 |
269 |
1-Bromo-2-(2,2-difluoroethylsulfinyl)benzene (Purity >95%)
At least 0.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
495 |
1995 |
4995 |
|
|
|
|
 |
191 |
3-Bromo-2-fluoro-phenol (Purity >95%)
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
125 |
245 |
495 |
1995 |
3995 |
|
|
|
|
 |
212 |
7-Bromo-2-methyl-1H-imidazo[4,5-c]pyridine (Purity >95%)
At least 1 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
|
1195 |
3995 |
9995 |
|
|
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
241 |
7-Bromo-3,4-dihydro-2H-benzo[b]oxepin-5-one (Purity >95%)
|
| Special Order*: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
|
195 |
950 |
2950 |
|
|
|
|
 |
281 |
[(4-bromo-3-chlorophenyl)amino]hydrazinomethane-1-thione (Purity >95%)
At least 1 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
95 |
115 |
465 |
|
|
|
|
|
 |
193 |
4-Bromo-3-methyl-isothiazol-5-ylamine (Purity >95%)
At least 25 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
495 |
1995 |
3995 |
|
|
|
|
 |
178 |
5-Bromo-3-methyl-isothiazole (Purity >95%)
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
395 |
950 |
2995 |
|
|
|
|
|
 |
241 |
3-Bromo-5-trifluoromethyl-pyridin-2-ylamine (Purity >95%)
At least 149.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
495 |
1995 |
3495 |
4495 |
|
|
|
 |
259 |
2-(3-Bromo-phenoxymethyl)-[1,3]dioxolane (Purity >95%)
At least 15 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
|
95 |
450 |
1750 |
|
|
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
259 |
2-(2-Bromo-phenoxymethyl)-[1,3]dioxolane (Purity >95%)
At least 20 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
|
95 |
450 |
1750 |
|
|
|
|
 |
239 |
1-(4-Bromo-phenyl)-1,3-dihydro-imidazol-2-one (Purity >95%)
At least 4.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
295 |
495 |
1995 |
5995 |
|
|
|
|
 |
239 |
4-(4-Bromo-phenyl)-1,3-dihydro-imidazol-2-one (Purity >95%)
At least 4.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
495 |
1495 |
2995 |
|
|
|
|
 |
224 |
4-(2-Bromo-phenyl)-oxazole (Purity >95%)
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 195 |
495 |
995 |
|
|
|
|
|
|
|
 |
197 |
(5-Bromo-pyridin-3-yl)-acetonitrile (Purity >95%)
|
| Special Order*: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
495 |
|
|
|
|
|
|
|
 |
210 |
8-Bromo-pyrido[3,4-b]pyrazine (Purity >95%)
At least 0.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
245 |
495 |
950 |
2995 |
6995 |
|
|
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
198 |
6-Bromo-[1,2,4]-triazolo[4,3-a]pyridine (Purity >95%)
At least 0.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
295 |
495 |
1695 |
3495 |
|
|
|
|
 |
242 |
7-Bromopyrido[2,3-b]pyrazine-2,3(1H,4H)-dione (Purity >95%)
At least 20 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
125 |
245 |
495 |
1995 |
3495 |
|
|
|
|
 |
221 |
4-bromothiophene-2-acetic acid (Purity >95%)
At least 0.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
145 |
295 |
495 |
1995 |
3995 |
|
|
|
|
 |
140 |
4-tert-Butyl-1,3-dihydro-imidazol-2-one (Purity >95%)
At least 15 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
395 |
1650 |
2950 |
|
|
|
|
 |
197 |
7-Chloro-3,4-dihydro-2H-benzo[b]oxepin-5-one (Purity >95%)
At least 30 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
|
195 |
950 |
2950 |
|
|
|
|
 |
144 |
(5-Chloro-pyridin-3-yl)-methanol (Purity >95%)
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
295 |
895 |
1850 |
4280 |
|
|
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
205 |
2-(4-Cyano-phenoxymethyl)-[1,3]dioxolane (Purity >95%)
At least 25 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
|
95 |
240 |
710 |
|
|
|
|
 |
397 |
2-Cyclobutyl-azepane oxalate (Purity >95%)
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
|
|
|
|
|
|
|
 |
139 |
2-Cyclobutyl-piperidine (Purity >95%)
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
295 |
995 |
2495 |
4995 |
|
|
|
|
 |
175 |
3-Cyclopropyl-1,3-dihydro-imidazo[4,5-b]pyridin-2-one (Purity >95%)
At least 0.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
395 |
895 |
2995 |
6995 |
|
|
|
|
 |
142 |
[1,4]Diazocane-5,8-dione (Purity >95%)
At least 5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
145 |
295 |
495 |
1950 |
|
|
|
|
|
 |
235 |
4-(2,2-Diethoxy-ethoxy)-benzonitrile (Purity >95%)
At least 10 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
80 |
95 |
195 |
850 |
|
|
|
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
192 |
3,5-Difluoro-4-chlorophenylboronic acid (Purity >95%)
At least 1 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
295 |
495 |
1995 |
4995 |
|
|
|
|
 |
224 |
3,5-Difluoro-4-difluoromethoxy-benzeneboronic acid (Purity >95%)
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
|
|
2495 |
4995 |
|
|
|
|
 |
188 |
3,5-Difluoro-4-methoxy-phenylboronic acid (Purity >95%)
At least 10.3 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
295 |
495 |
1995 |
4995 |
|
|
|
|
 |
202 |
2,2-Difluoro-benzo[1,3]dioxole-4-boronic acid (Purity >95%)
At least 10 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
250 |
495 |
895 |
3995 |
6995 |
|
|
|
|
 |
202 |
3-(2,2-Difluoroethoxy)phenylboronic acid
(Purity >90%)
At least 1 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
495 |
795 |
1995 |
|
|
|
|
|
|
 |
112 |
4,5-Dimethyl-1,3-dihydro-imidazol-2-one (Purity >95%)
At least 5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
495 |
1950 |
2950 |
|
|
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
150 |
2,6-dimethyl-pyridine-3-boronic acid (Purity >90%)
At least 25 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
295 |
495 |
850 |
2995 |
4995 |
|
|
|
|
 |
186 |
cis, trans, trans-3,5-Dioxa-bicyclo[5.1.0]octane-8-carboxylic acid ethyl ester (Purity >95%)
At least 5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
395 |
1950 |
|
|
|
|
|
 |
280 |
1-[1,3]Dioxolan-2-ylmethyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole (Purity >95%)
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 80 |
95 |
145 |
395 |
1495 |
3995 |
|
|
|
|
 |
198 |
1,4-Dithia-7-aza-spiro[4.4]nonane hydrochloride (Purity >95%)
At least 20 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
145 |
195 |
295 |
995 |
2995 |
|
|
|
|
 |
212 |
1,4-Dithia-7-aza-spiro[4.5]decane hydrochloride (Purity >95%)
At least 25 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
145 |
195 |
295 |
995 |
2995 |
|
|
|
|
 |
212 |
1,4-Dithia-8-aza-spiro[4.5]decane hydrochloride (Purity >95%)
At least 15 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
650 |
1900 |
3350 |
|
|
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
226 |
1,4-Dithia-8-aza-spiro[4.6]undecane, hydrochloride (Purity >90%)
At least 20 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
295 |
995 |
3995 |
|
|
|
|
 |
175 |
4-Ethyl isatin (Purity >95%)
At least 15 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
85 |
135 |
395 |
1450 |
3550 |
|
|
|
|
 |
175 |
6-Ethyl isatin (Purity >95%)
At least 1 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
85 |
135 |
395 |
1450 |
3550 |
|
|
|
|
 |
208 |
5-Fluoro-2-trifluoromethyl-phenylboronic acid (Purity >95%)
At least 10 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
295 |
495 |
1995 |
5995 |
|
|
|
|
 |
208 |
4-Fluoro-2-trifluoromethyl-phenylboronic acid (Purity >95%)
At least 15 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
295 |
495 |
1995 |
4995 |
|
|
|
|
 |
126 |
6-Fluoro-4-methyl-pyridin-3-ylamine (Purity >95%)
At least 74.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
145 |
295 |
995 |
1995 |
2495 |
|
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
208 |
3-Fluoro-4-trifluoromethyl-phenylboronic acid (Purity >95%)
At least 25 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
295 |
495 |
995 |
2995 |
|
|
|
|
 |
198 |
2-(2-Fluoro-phenoxymethyl)-[1,3]dioxolane (Purity >95%)
At least 20 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
|
95 |
450 |
1750 |
|
|
|
|
 |
198 |
2-(4-Fluoro-phenoxymethyl)-[1,3]dioxolane (Purity >95%)
At least 20 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
|
95 |
450 |
1750 |
|
|
|
|
 |
198 |
2-(3-Fluoro-phenoxymethyl)-[1,3]dioxolane (Purity >95%)
At least 20 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
|
95 |
450 |
1750 |
|
|
|
|
 |
178 |
4-(4-Fluoro-phenyl)-1,3-dihydro-imidazol-2-one (Purity >95%)
At least 1 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
145 |
245 |
495 |
1995 |
3995 |
|
|
|
|
 |
112 |
3-Fluoroazetidine Hydrochloride (Purity >95%)
At least 10 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 195 |
295 |
595 |
995 |
2995 |
6995 |
|
|
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
138 |
1,3,4,5,6,7-Hexahydro-benzoimidazol-2-one (Purity >95%)
At least 10 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
495 |
2295 |
4495 |
|
|
|
|
 |
188 |
2-Hydrazino-5-bromopyridine (Purity >95%)
At least 150 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
|
295 |
950 |
1950 |
2495 |
|
|
|
 |
254 |
2-Hydroxy-5-imidazo[1,2-a]pyrimidin-2-yl-benzamide (Purity >95%)
At least 9.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
185 |
395 |
895 |
|
|
|
|
|
 |
146 |
4-Hydroxy-cinnoline (Purity >95%)
At least 14.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
495 |
1995 |
3495 |
|
|
|
|
 |
214 |
5-(3-Hydroxyphenyl)-pyridine-3-carboxamide (Purity >95%)
At least 0.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
295 |
495 |
995 |
|
|
|
|
|
|
 |
220 |
4-Imidazo[1,2-a]pyrimidin-2-yl- benzonitrile (Purity >95%)
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
135 |
195 |
|
|
|
|
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
119 |
Imidazo[1,2-b]pyridazine (Purity >95%)
At least 24.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
495 |
1495 |
3495 |
|
|
|
|
 |
225 |
4-Imidazo[2,1-b]thiazol-6-yl-benzonitrile (Purity >95%)
At least 0.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
105 |
165 |
245 |
|
|
|
|
|
|
 |
307 |
1-(2-Methoxy-benzenesulfonyl)-4-methyl-piperazine; hydrochloride (Purity >95%)
At least 1 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
395 |
1295 |
|
|
|
|
|
 |
153 |
2-methyl-3-fluoro-phenylboronic acid (Purity >95%)
At least 1 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
295 |
495 |
1995 |
4995 |
|
|
|
|
 |
204 |
2-Methyl-3-trifluoromethyl-phenylboronic acid (Purity >95%)
At least 1 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
245 |
495 |
850 |
3495 |
7995 |
|
|
|
|
 |
243 |
2-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzonitrile (Purity >95%)
At least 20 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
145 |
245 |
495 |
2295 |
4995 |
|
|
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
204 |
2-Methyl-5-trifluoromethyl-phenylboronic acid (Purity >95%)
At least 4.1 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
245 |
395 |
850 |
3495 |
5995 |
|
|
|
|
 |
150 |
2-Methyl-[1,2,6]thiadiazinane 1,1-dioxide (Purity >95%)
At least 9.5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
145 |
295 |
495 |
1995 |
3495 |
|
|
|
|
 |
134 |
(3-Methylenecyclobutyl)methanamine hydrochloride (Purity >95%)
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
|
950 |
2550 |
3950 |
|
|
|
|
 |
240 |
2-(4-Nitro-phenyl)-imidazo[1,2-a] pyrimidine (Purity >92%)
At least 1 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
135 |
195 |
|
|
|
|
|
|
 |
240 |
2-(3-Nitro-phenyl)-imidazo[1,2-a] pyrimidine (Purity >96%)
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
135 |
195 |
|
|
|
|
|
|
 |
134 |
(1-Oxy-pyridin-3-yl)-acetonitrile (Purity >95%)
At least 5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
295 |
1350 |
3950 |
|
|
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
186 |
(1-Phenyl-ethyl)-phosphonic acid (Purity >95%)
At least 1 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
495 |
850 |
2450 |
3950 |
|
|
|
|
 |
163 |
6,7,8,9-Tetrahydro-5H-cyclohepta[b]pyridine-N-oxide (Purity >95%)
At least 1 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
159 |
495 |
1995 |
4995 |
|
|
|
|
 |
155 |
4,5,6,7-Tetrahydro-thiazolo[5,4-c]pyridin-2-ylamine (Purity >95%)
At least 9.9 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
295 |
495 |
1995 |
3995 |
|
|
|
|
 |
290 |
4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-1-thiophen-2-ylmethyl-1H-pyrazole (Purity >95%)
At least 1 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
295 |
495 |
1995 |
3495 |
|
|
|
|
 |
285 |
3-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyrazol-1-ylmethyl]-pyridine (Purity >95%)
At least 5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
395 |
950 |
1995 |
3495 |
|
|
|
|
 |
285 |
2-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyrazol-1-ylmethyl]-pyridine (Purity >95%)
At least 1 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
295 |
495 |
1995 |
3995 |
|
|
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
258 |
6-(4,4,5,5-Tetramethyl1,3,2-dioxaboralan-2-yl)-2,3-dihydroinden-1-one (Purity >95%)
At least 1 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
245 |
495 |
995 |
3495 |
5995 |
|
|
|
|
 |
136 |
Thieno[2,3-d]pyridazine (Purity >95%)
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
495 |
1995 |
4995 |
|
|
|
|
 |
172 |
Thiomorpholine-1,1-dioxide hydrochloride (Purity >90%)
At least 5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
95 |
195 |
395 |
1695 |
3250 |
|
|
|
|
 |
207 |
2-(trifluoromethyl)-3-fluoro-phenylboronic acid (Purity >95%)
At least 5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 195 |
295 |
395 |
1095 |
2995 |
|
|
|
|
|
 |
208 |
3-(Trifluoromethyl)-5-fluoro-phenylboronic acid (Purity >95%)
At least 5 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
145 |
245 |
495 |
1495 |
2995 |
|
|
|
|
 |
203 |
3-(trifluoromethyl)-5-methyl-phenylboronic acid (Purity >95%)
At least 15 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
295 |
595 |
950 |
2495 |
3995 |
|
|
| Catalog Number |
Structure |
FW |
Chemical Name and % Purity |
Please scroll down for more structures |
|
|
 |
208 |
3-Trifluoromethyl-4-fluoro-phenylboronic acid (Purity >95%)
At least 50 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
75 |
145 |
295 |
995 |
1995 |
2495 |
|
|
|
 |
205 |
6-Trifluoromethyl-pyridine-2-carboxylic acid methyl ester (Purity >95%)
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 75 |
125 |
245 |
495 |
1595 |
2995 |
|
|
|
|
 |
191 |
4-Trifluoromethyl-pyridine-3-boronic acid (Purity >95%)
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
395 |
695 |
1995 |
4995 |
|
|
|
|
 |
191 |
2-Trifluoromethyl-pyridine-5-boronic acid (Purity >95%)
At least 10 grams in stock
|
| In Stock: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| 95 |
195 |
295 |
495 |
1995 |
3995 |
|
|
|
|
 |
197 |
5-Bromo-imidazo[1,2-a]pyridine (Purity >95%)
|
| Special Order*: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
|
|
|
1295 |
2495 |
|
|
|
|
 |
164 |
4-Bromo-isothiazole (Purity >95%)
|
| Special Order*: Price in US$ |
10 mg |
100 mg |
250 mg |
1g |
5g |
20g |
50g |
| |
95 |
295 |
495 |
1995 |
3995 |
|
|
Recently, a set of rules has been developed to help identify small molecules suited for the fragment-based lead discovery. This novel approach to drug discovery involves screening libraries of low-molecular weight fragments for their ability to interact with a macromolecular target through protein x-ray crystallography or NMR. Congreve, Carr, Murray and Jhoti determined that small molecules that obey the "Rule of Three" are most suited to this approach: FW < 300, hydrogen bond donors <=3, hydrogen bond acceptors <=3, ClogP <=3. Focus Synthesis offers RubyRO3 building blocks, a set of over 150 building synthons and precursors that meet the basic Rule of Three criteria. More than 80% of these are predicted to be stable in physiological buffers, and could be used directly as screening compounds particularly suited for fragment-based lead discovery. 100% of the "Rule of Three" products are ideal lead candidates, particularly well suited as precursors for lead-like and drug-like molecules to keep drug discovery pipelines full of high quality drug candidates. Purchase RubyRO3 chemicals to accelerate your fragment-based screening progam.