Explore Chemical Space

Focus Synthesis is a chemical distributor and manufacturer offering small molecule synthons, building blocks, and heterocycles with highly distinctive chemical structures to help you explore chemical space. In addition to providing a catalog of rare laboratory chemicals for organic synthesis and drug discovery, Focus Synthesis also provides custom synthesis and synthon design services.

The price of large chemical diversity voids in a corporate compound collection can literally be billions of dollars: the price of losing out to a competitor who has the right molecule and files an earlier patent application, or the price of failure in Phase III or IV because more suitable chemical structures were unavailable in the drug discovery phase. When a lack of drug candidate alternatives prevents development of a less toxic alternative, the price of inadequate diversity is also measured in human lives.

For pharmaceutical chemistry programs, whether making broad libraries, focused libraries, or individual compounds, voids in chemical space for your precursors result in larger, more extensive voids for your drug candidates. Focus Synthesis synthons and building blocks are designed to fill chemical diversity voids, so that your organic synthesis will yield more thorough coverage of chemical space and more diversity. Focus Synthesis uses cheminformatics to design drugable synthons and building blocks that are as distinct as possible from the offerings of other chemical distributors. Purchase rare chemicals from Focus synthesis to accelerate medicinal chemistry and build a truly diverse, robust corporate compound collection.

Several examples of Focus Synthesis products are shown below, with the rare substructures highlighted in red. These molecules are in a class by themselves, in that they are the only molecules in the Available Chemical Directory (Symyx Technologies, Inc.) that contain the rare substructure.